Marking the official start of construction on the Mount Sinai Tisch Cancer Hospital, a ceremonial groundbreaking with visionary philanthropic leaders James S. Tisch, Chairman Emeritus of the Mount Sinai Health System Boards of Trustees, and Merryl H. Tisch, EdD, was held on Monday, June 1. The Tisches’ transformational support has brought this milestone project to life. With key Mount Sinai leaders and project partners in attendance, the gathering celebrated not only the beginning of construction, but also a shared commitment to advancing cancer care for patients and families from across New York City and the world.
From left: Brendan G. Carr, MD, MA, MS; Merryl H. Tisch, EdD; and James S. Tisch, Chairman Emeritus of the Mount Sinai Health System Boards of Trustees
In his remarks, Mount Sinai CEO Brendan G. Carr, MD, MA, MS, Professor and Kenneth L. Davis, MD Distinguished Chair, reflected on the intentionality behind the Tisches’ extraordinary gift and the lasting difference it will make for people facing cancer. “This will be an incredible, long-standing testament to your family’s gift to New York and beyond, and especially to the patients who have cancer,” he said. “All of our families have been touched by cancer, I’m certain. And it is a massive thing to get comfort during people’s most trying times. On behalf of Mount Sinai, thank you.”
Opening in 2030 on Mount Sinai’s Upper East Side campus, the Mount Sinai Tisch Cancer Hospital will build on the Mount Sinai Tisch Cancer Center’s distinction as a National Cancer Institute-designated Comprehensive Cancer Center—the highest designation awarded to cancer centers in the United States, placing Mount Sinai among the top one percent nationally. The new hospital is envisioned as an ultra-modern, deeply compassionate environment where breakthrough science and whole-person care are closely connected, bringing patients, families, clinicians, and researchers together in one singular place of hope and healing.
Mr. Tisch spoke warmly about his family’s long partnership with Mount Sinai and their pride in supporting a project that will shape its future. “Mount Sinai is in my heart,” he said, recalling nearly four decades of involvement with the institution. Of the new hospital, he added, “We decided that this was a great family legacy to be behind... we are excited about this hospital that’s being built... the research that’s being done... and the people who are being trained here at Mount Sinai. I think that Mount Sinai’s future looks fabulous going forward.”
Dr. Carr also underscored the extraordinary scale of Mount Sinai’s cancer program and the patient-centered mission at the heart of this investment. He noted that Mount Sinai recorded 300,000 ambulatory oncology visits last year across 13 locations, supported by 280 cancer specialists, and cared for nearly 10,000 people diagnosed with cancer or being evaluated for it. “Just a reminder that everything that we do is rooted in patient care,” he said.
At its heart, the groundbreaking was a celebration of generosity, vision, and shared purpose. It marks the beginning of a project that will transform the experience of cancer care at Mount Sinai—creating a warm, welcoming, and state-of-the-art hospital where patients are surrounded by expertise, innovation, and the comfort of those who care for them. For the Tisch family, Mount Sinai leadership, and all those gathered, the moment offered a powerful glimpse of what the new hospital will make possible for generations to come.

A 3-D architectural model of the Mount Sinai Tisch Cancer Hospital is on public display at The Mount Sinai Hospital, located at 1468 Madison Avenue.

From left: Evan Flatow, MD, Executive Vice President for Clinical Affairs for the Mount Sinai Health System, and
Dean for Clinical Affairs at Icahn School of Medicine at Mount Sinai; Brendan G. Carr, MD, MA, MS, CEO and Professor and Kenneth L. Davis, MD Distinguished Chair; David L. Reich, MD, Chief Clinical Officer, Mount Sinai Health System, and President, The Mount Sinai Hospital; James S. Tisch, Chairman Emeritus of the Mount Sinai Health System Boards of Trustees; and Eric J. Nestler, MD, PhD, Anne and Joel Ehrenkranz Dean of the Icahn School and Executive Vice President and Chief Scientific Officer of the Mount Sinai Health System.

From left: David L. Reich, MD, Chief Clinical Officer, Mount Sinai Health System, and President, The Mount Sinai Hospital; Luis M. Isola, MD, Physician-in-Chief, Tisch Cancer Hospital, Professor of Medicine, Hematology and Medical Oncology; Brendan G. Carr, MD, MA, MS; Evan Flatow, MD; Margaret Pastuzsko, President and Chief Operating Officer, Mount Sinai Health System; James S. Tisch; Eric J. Nestler, MD, PhD; Fran Cartwright, PhD, RN-BC, AOCN, FAAN, Vice President of Nursing, Mount Sinai Health System Oncology Services, and Associate Professor, Department of Medicine, Icahn School; Ramon E. Parsons, MD, PhD, Director of the Tisch Cancer Center, Dean for Cancer Research, Ward-Coleman Chair in Cancer Research, and Chair of the Department of Oncological Sciences, Icahn School.


From left: David L. Reich, MD; Brendan G. Carr, MD, MA, MS; and Ashutosh (Ash) Tewari, MD, MBBS, MCh, FRCS (Hon.), DSc (Hon.), Kyung Hyun Kim, MD Chair in Urology, Surgeon-in-Chief, the Tisch Cancer Hospital, Professor and Chair, Milton and Carroll Petrie Department of Urology, Director of Center of Excellence for Prostate Cancer, Tisch Cancer Center.
About the new Mount Sinai Tisch Cancer Hospital
Designed around what matters most to patients and loved ones, the Tisch Cancer Hospital will include 72 acuity-adaptable, fully ADA-accessible private rooms across four floors, with the flexibility for each room—or even entire floors—to convert to ICU-level care if needed. A 24-hour oncology urgent care unit will offer an alternative to the stress of a typical emergency department, helping patients access specialized care quickly and safely. Every patient room will also feature digital tools for education, nutrition, and care-team information, reinforcing an experience that is as supportive and seamless as it is clinically advanced.
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