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When you give to Mount Sinai, you’re not just supporting globally recognized science and medicine—you’re investing in a model that turns philanthropy into measurable, accelerated impact for patients and communities. Mount Sinai is designed to operate efficiently and effectively, ensuring that your contribution makes a significant and immediate impact.

Philanthropy that accelerates discovery

Philanthropy at Mount Sinai is designed to do what traditional funding often can’t: move early, bet on bold ideas, and build momentum. Donor support launches promising concepts, generates proof-of-concept data, recruits talent, and speeds collaboration—so discoveries can advance toward patients sooner. 

It also strengthens Mount Sinai’s ability to compete for major external support: in fiscal year 2025, researchers at the Icahn School of Medicine at Mount Sinai applied for and received more NIH awards than any other freestanding academic medical center. This can only happen when philanthropy helps recruit top talent and fund early-stage ideas.

Philanthropy as Force-Multiplier

Philanthropy was the force-multiplier that allowed investigators the freedom and flexibility to explore a moonshot idea. With proof-of-concept thus established, it is now supported by a six-million dollar grant from the National Institutes of Health (NIH).

FBI Donor Ram Sundaram poses with Drs. Goosens and Zaidi

Recognized for impact, not bureaucracy

Mount Sinai is ranked #20 on Forbes’ list of The 100 Largest U.S. Charities (2025)—and #1 among academic medical centers on the list. That recognition reflects disciplined fundraising: the average fundraising efficiency for the list’s top charities is 91% - which Mount Sinai exceeds with a fundraising efficiency of 97%, ensuring your philanthropic donors aren’t caught up in excess administrative overhead. You can learn more about how Forbes evaluated the non-profits here.

Donors deserve confidence that their giving is used responsibly and as intended. Mount Sinai’s scale and efficiency reflect a disciplined approach to operations and a deep commitment to directing resources toward our mission and outcomes. 

Our academic medical center model

Mount Sinai integrates world-class clinical care, scientific discovery, and medical education—so ideas move quickly from hypothesis to healing, and tomorrow’s leaders train in the same environment where breakthroughs are made. For donors, that integration matters: it brings physicians and scientists into close partnership, supports specialized expertise at scale, strengthens the pipeline of future clinicians and scientists, and helps communities respond to emerging health needs.

And when discoveries have the potential to scale beyond a single institution, Mount Sinai Innovation Partners helps connect faculty with collaborators and strategic partners so therapies, technologies, and new approaches can reach more people.

Additionally, academic medical centers are engines of regional jobs education, and innovation. As one of New York City’s largest employers and a major driver of research activity, Mount Sinai strengthens the city’s resilience—so your support doesn’t just help our research and ability to provide compassionate care to New Yorkers, it becomes part of a wider economic engine. 

Built by philanthropy—and still shaped by it

Mount Sinai was founded by philanthropically minded New Yorkers committed to ensuring access to excellent care. That origin story still defines how we operate today: donors are true partners in advancing science, training the next generation of physicians and scientists, and expanding compassionate care across New York City and beyond.

Since 1852, Mount Sinai has been committed to serving New York’s underserved communities—advancing research that tackles health inequities and delivering high-quality care through neighborhood-based programs and clinics. Philanthropy helps us focus on population and community health so progress is built for everyone, not just for the few.